Indole-3-carboxamides are a class of designer drugs which are known as synthetic cannabinoids. Examples of these include compounds such as 5F-APICA (“STS-135”). SGT-67 (5F-CUMYL-PICA) is an analogue of 5F-APICA with the N-adamantyl group replaced by an N-cumyl group. 5F-CUMYL-PICA is believed to act as an agonist at cannabinoid receptors. This product is intended for forensic and research applications.
sgt-67 is a new research chemical in the family of synthetic cannabinoids. the iupac name for the chemical is 1-(5-fluoropentyl)-n-(2-phenylpropan-2-yl)-1h-indole-3-carboxamide. the chemical formula is c23h27fn2o and the molecular mass is 366.02. sgt-67 often referred to as 5f-cumyl-pica.
one study conducted on sgt-67 characterized the metabolism as well as the clearance of the research chemical using rat and human liver microsomes along with hepatocytes, which were used to compare to urine sampling and in vivo rat plasma. the study also examined hypothermia. the incubation with the microsomes showed fast metabolic clearance however, in the metabolism in vivo took longer which allowed detection in the rat plasma. the research chemical did show hypothermic effects with 28 metabolites able to be identified.
other research shows that sgt-67 is an agonist at the receptors known as cannabinoid. being an analog of similar compound the difference noted was that an n-cumyl group replaced the n-adamantyl group. for laboratories that wish to conduct studies on sgt-67, it is important to purchase from a research chemical manufacturer that includes all data regarding how to safely handle the chemical as well as how to protect the shelf life of the chemical.
more research needs to be conducted in laboratories until data can be compiled to learn compound properties. currently compound only intended for scientific and forensic research and is not for human consumption.
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